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GPB 2025

Revolutionizing agricultural sustainability with CRISPR-enhanced crop resilience

Tsitsi Antonet Mutandiwa, Speaker at Plant Biology Conferences
University of South Africa, South Africa
Title : Revolutionizing agricultural sustainability with CRISPR-enhanced crop resilience

Abstract:

Global agriculture faces unprecedented challenges due to climate change, including increased drought, pestilence, and disease pressures. In response, this study leverages CRISPR-Cas9 genome editing technology to develop crop varieties with enhanced resilience and sustainability. Our research focuses on two main objectives: increasing the drought tolerance of staple crops and improving resistance to both pests and pathogens. Our methodology involved the identification and targeted modification of specific genes linked to water retention and stress response pathways in plants such as maize, rice, and wheat. Using CRISPR-Cas9, we introduced mutations designed to enhance the expression of these genes, thereby improving the plants' intrinsic ability to withstand drought conditions. Concurrently, we targeted genes involved in defence mechanisms against pests and pathogens, aiming to reduce the need for chemical pesticides and decrease agriculture's environmental footprint. Preliminary field trials have demonstrated that CRISPR-enhanced crops exhibit significantly improved growth and yield under controlled drought conditions. Additionally, these crops showed increased resistance to common pests and diseases, confirming the potential of genetic interventions in achieving sustainable agricultural practices. The implications of this research are profound, offering a viable biotechnological solution to some of the most critical issues facing modern agriculture. Increasing crop resilience through genetic enhancements can secure food supplies for future generations while minimising environmental impact. This study advances our understanding of plant genetics and showcases the potential of CRISPR technology as a cornerstone for sustainable agriculture.

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